You can detach a datastore from one or more hosts. After a datastore is detached from a host, it is no longer available to that host.
From the Navigator pane, or the Objects tab, double-click and select the storage system with the datastore to be detached.
Click the Manage tab, and then click the Datastores tab.
Click the Configure Datastore icon.
Click the Detach Datastore option, and then click Next.
Select the datastore that you want to detach (only clusters and hosts where the datastore is attached are displayed). Click Next.
Select the cluster or host, and then click Next.
Review the summary details, and then click Finish.